Subprojects
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SP 1: Protein-protein interaction networks in neurodegenerative disorders Prof. Dr. Erich Wanker The subproject will focus on the generation and bioinformatic analysis of protein-protein interactions (PPI). These data will be combined with the results of... >> read more |
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SP 2: Protein-protein interaction screening by quantitative proteomics Dr. Matthias Selbach In order to understand neurodegenerative disease networks extensive information of protein-protein interactions (PPIs) is essential. Genetic (e.g. Y2H) and biochemical... >> read more |
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SP 3: Modulation of protein-protein interaction networks by phosphorylation Dr. Ulrich Stelzl In eukaryotic cells, the phosphorylation of proteins plays an important role. First of all, signal transduction inside the cell is often achieved by fast covalent modifications of... >> read more |
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SP 4: Classification of phenotype-to-genotype relationships for neurodegenerative diseases Prof. Dr. Josef Priller We aim to define syndrome families in an attempt to help uncover new relationships between genes, proteins and the interactome. We shall standardise... >> read more |
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SP 5: Modulation of protein complex composition and function through stress and neurodegenerative disease signalling PD Dr. Bodo M.H. Lange The aim of this subproject is to analyse the consequence of modulation of neurodegenerative disease relevant protein-protein interactions and disease specific genetic... >> read more |
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SP 6: Gene expression signatures for neurodegenerative disease processes Dr. Wilfried Nietfeld A fundamental challenge throughout biomedicine is the need to establish the relationship among physiological disease processes and the action of small molecule... >> read more |
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SP 7: Systematic phenotype profiling with RNAi and small molecules Prof. Dr. Michael Boutros Our research goal is a systems-level approach to analyse signalling pathways playing an important role in neurodegenerative diseases. In order to identify... >> read more |
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SP 8: Data integration and generation of phenotype-protein-drug interaction networks for neurodegenerative diseases Dr. Miguel Andrade & Prof. Dr. Peer Bork The goal of this subproject is the development of a project database for all experimental data generated by the project partners. This information will be combined... >> read more |
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SP 9: Management of the IG NeuroNet Prof. Dr. Erich Wanker In IG NeuroNet, a total of 8 subprojects are coordinated by Professor Erich Wanker. The coordinator is supported by a project administrator in all... >> read more |
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Interaktom Prof. Dr. Erich Wanker The main goal of this project is the delevelopment of the scientific platform "Interaktom" for systematic protein interaction studies. Through the platform... >> read more |